我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|Table of Contents|

CrO3/SiO2固载氧化剂对脱氢枞胺衍生物B环的氧化(PDF)

《南京林业大学学报(自然科学版)》[ISSN:1000-2006/CN:32-1161/S]

Issue:
2012年03期
Page:
101-104
Column:
研究论文
publishdate:
2012-05-30

Article Info:/Info

Title:
Oxidation on ring B of dehydroabietylamine derivatives using CrO3/SiO2 solid-supported oxidizing reagent
Author(s):
CHEN Yong1 LIN Zhongxiang2*
1. College of Science, Nanjing Forestry University, Nanjing 210037, China; 2. College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China
Keywords:
N-benzoyl-dehydroabietylamine oxidation N-benzoyl-dehydroabietylamine-7-one CrO3/SiO2 oxidizing reagent
Classification number :
TQ 351
DOI:
10.3969/j.jssn.1000-2006.2012.03.021
Document Code:
A
Abstract:
A supported oxidant CrO3/SiO2 was prepared by absorbing the CrO3 on silicon gel, and its oxidation characteristics was investigated for the oxidation of N-benzoyl-dehydroabietylamine to N-benzoyl-dehydroabietylamine-7-one in this paper. Effects of solvent types and quantities, reaction temperature, loading amount and oxidant dosage on the yield were examined. The test result indicated that N-benzoyl-dehydroabietylamine-7-one can be obtained with yield of 60% by oxidation of 1 g(2.57 mmol)N-benzoyl-dehydroabietylamine in the present of 2 equimolar amount of CrO3/SiO2(loading amount 2 mmol/g)in 50 mL cyclohexane under the reflux temperature for 8 h. This reagent is easily prepared, it can be used in the field of allylic oxidation in relatively high oxidation selectivity, yields with simple procedure and easy purifications.

References

[1] 饶小平,宋湛谦,高宏.脱氢枞胺及其衍生物的研究与应用进展[J].化学通报,2006,69(3):168-172.
[2] Wang H S, Zhang R C, Zhao S L, et al. Synthesis and application of dehydroabietylisothiocyante as a new chiral derivatizing agent for the enantiomeric separation of chiral compounds by capillary electrophoretic[J]. Analytica Chimica Acta, 2006, 560(1-2): 64-68.
[3] 黄春林,黄科林,吴睿,等.脱氢枞胺的性能和应用[J].化工技术与开发,2010,39(2):21-25.
[4] 陈泳,林中祥,张丹红.脱氢枞胺(4-羟基)水杨醛Schiff碱β-环糊精包合物的制备与表征[J].南京林业大学学报:自然科学版,2011,35(1):62-66.
[5] Rao X P, Song Z Q, He L. Synthesis and antitumor activity of novel α-aminophosphonates from diterpenic dehydroabietylamine[J]. Heteroatom Chemistry, 2008, 19(5): 512-515.
[6] Li A P, She X G, Zhang J Y, et al. Synthesis of C-7 oxidized abietane diterpenes from racemic ferruginyl methyl ether[J]. Tetrahedron, 2003, 59(20): 5737-5741.
[7] González M A, Pérez-Guaita D, Correa-Royero J, et al. Synthesis and biological evaluation of dehydroabietic acid derivatives[J]. European Journal of Medicinal Chemistry, 2010, 45(2): 811-816.
[8] Xiong Y, Wang K W, Pan Y J, et al. Isolation, synthesis, and anti-tumor activities of a novel class of podocarpic diterpenes[J]. Bioorganic & Medicinal Chemistry Letters, 2006, 16(4): 786-789.
[9] 陈泳,林中祥.N-苯甲酰基-脱氢枞胺-7-酮的合成及其对雄激素受体活性的研究[J].林产化学与工业,2009,29(增刊):121-124.
[10] 李谦和,陈亮,尹笃林,等.Cr载体氧化试剂的制备和应用研究-微波促进三氧化铬/硅胶氧化试剂的制备[J].湖南师范大学自然科学学报,2004,27(4):55-58.
[11] 史黎薇.铬化合物对健康影响的研究进展[J].卫生研究,2003,32(4):410-412.
[12] 王代芝.铬渣和含铬废水的处理综述[J].辽宁化工,2004,33(10):615-616.
[13] 颜家保,王光辉,王敬,等.用亚硫酸钠处理硅钢含铬废水的实验研究[J].北方环境,2005,30(2):21-23.
[14] 张楠,薛改凤,张垒,等.钢铁厂含铬废水处理技术研究进展[J].工业用水与废水,2010,41(5):6-8.
[15] 周建国,李海明,陈培丽.绿色有机合成研究进展[J].天津化工,2009,23(6):1-4.
[16] 李谦和,匡玲玲,彭沙,等.Cr载体氧化试剂的制备和应用研究-紫苏醇选择氧化合成紫苏醛[J].湖南师范大学自然科学学报,2007,30(3):64-79.
[17] Monteiro M C S, Silvestre J D, Silva M S, et al. Synthesis and structural characterisation of ring B oxidised derivatives of dehydroabietic acid[J]. New Journal of Chemistry, 2001, 25(8): 1091-1097.

Last Update: 2012-05-30