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6-(2-(3,3-二甲基噁丙环-2-基)乙基) 萘-1,4-二酮的合成(PDF)

《南京林业大学学报(自然科学版)》[ISSN:1000-2006/CN:32-1161/S]

Issue:
2016年01期
Page:
111-116
Column:
研究论文
publishdate:
2016-01-31

Article Info:/Info

Title:
Synthesis of 6-(2-(3,3-dimethyloxiran-2-yl)ethyl)naphthalene-1,4-dione
Article ID:
1000-2006(2016)01-0111-06
Author(s):
LUO Jinyue1HAN Li1LU Qiang1LIU Huafeng1LIU Zuguang2
1. Jiangsu Key Lab of Biomass-based Green Fuels and Chemicals, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China;
2. Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Nanning 530006, China
Keywords:
naphthalenediquinone naphthalenedione epoxidation
Classification number :
TQ254
DOI:
10.3969/j.issn.1000-2006.2016.01.018
Document Code:
A
Abstract:
An efficient and practical method for the synthesis of 6-(2-(3,3-dimethyloxiran-2-yl)ethyl)naphthalene-1,4-dione by utilizing epoxidation of 6-(4-methylpent-3-en-1-yl)naphthalene-1,4-dione withperacetic acid as an oxidant was described. The structure of the product was determined by 1H-NMR, FT-IR and GC-MS analyses. Effects of solvent, reaction time, temperature and the ratio of the starting material, oxidant and sodium bicarbonate on conversion rate of the starting material and yield of the product were examined, and the optimal conditions were determined as follows: the molar ratio of 6-(4-methylpent-3-en-1-yl)naphthalene-1,4-dione/peracetic acid/sodium bicarbonate was 1:3:1.2,chloroform was used as the solvent, reaction temperature was 30 ℃, and reaction time was 5 h. The yield of 6-(2-(3,3-dimethyloxiran-2-yl)ethyl)naphthalene-1,4-dione reached 90.7% at aforesaid conditions.

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Last Update: 2016-02-25