Abstract: In this paper, the physical and mechanical properties of MDF were researched by the cloy process and various fire retadants were put into experiments. The effect of different fire retardants on physiomechanical and fire resistance of MDF was reflected, and then, based on analysis, the regression curves were obtained.Through experiments, the optimum pressing variables of MDF with APP were found; resin content was 10% , fire retardant content 7% , pressing temperature 140℃, pressing time 6 min. The optimum conditions of MDF with MDFP were : resin content was 8% , fire retardant content 10% , pressing temperature 140℃ , pressing time 6 min. The physical and mechanical properties of two kinds of MDF reached the first class of GB, and their fire-retarding properties were also the first class of TIS D 1322-77.