为了获得高活性的木材防腐剂,以1,3-二氯苯为原料,依次经过傅克酰基化、烷基化、环氧化及开环反应得到6种三唑类化合物Y-4(a-f),且所有化合物的结构经过MS和1H-NMR确定; 采用滤纸片法对常见的两种霉菌和两种木腐菌进行活性抑菌实验。结果表明:6种化合物中,Y-4d表现出的抗菌谱较广,对木材霉菌和腐朽菌都有抑制作用,但对腐朽菌的抑制效果不如Y-4c和Y-4f,Y-4c和Y-4f对木材腐朽菌表现出较强的抑制能力。
Abstract
In order to get a wood preservative with higher efficiency, six compounds Y-4(a-f)were synthesized using 1, 3-dichlorobenzene as the starting material by Friedel-crafts acetylation, alkylation, epoxidation, and ring-opening reaction. The structures of these compounds were determined by MS and 1H-NMR. Antifungal activities of these compounds were evaluated by two moulds and two decay fungi with Filter paper diffusion. The results indicated that Y-4d had a broad spectrum of antibacteria on moulds and decay fungi, but Y-4c and Y-4f had better antibacterial effect on decay fungi.
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基金
收稿日期:2013-06-08 修回日期:2013-09-24
基金项目:国家林业公益性行业科研专项项目(201104032)
第一作者:燕乐乐,硕士生。*通信作者:刘幸平,教授。E-mail: xpliu1955@163.com。。
引文格式:燕乐乐,刘幸平,程康华,等. 三唑类化合物的合成及抑菌活性[J]. 南京林业大学学报:自然科学版,2014,38(2):161-164.
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