A model for linkage disequilibrium analysis in an autotetraploid natural population

FENG Sisi, WANG Jianxin, PANG Xiaoming, WU Rongling

JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2014, Vol. 38 ›› Issue (04) : 29-33.

PDF(1388885 KB)
PDF(1388885 KB)
JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2014, Vol. 38 ›› Issue (04) : 29-33. DOI: 10.3969/j.issn.1000-2006.2014.04.006

A model for linkage disequilibrium analysis in an autotetraploid natural population

  • FENG Sisi1, WANG Jianxin1,2, PANG Xiaoming1, WU Rongling1*
Author information +
History +

Abstract

More than 50% of angiosperms are polyploidy, or have experienced genome doubling in their evolutionary history. Thus, polyploids provide a valuable tool to study the genetics and evolution of plants. Linkage disequilibrium analysis has been widely used to infer the genetic structure, differentiation and diversity of natural populations, but its basic principle was found on a diploid population. In this article, we have derived a model for linkage disequilibrium analysis between a pair of molecular markers for the first time based on meiotic properties of autotetraploids. Computer simulation has been performed to examine the usefulness of the new model and determine the condition of its utilization.

Cite this article

Download Citations
FENG Sisi, WANG Jianxin, PANG Xiaoming, WU Rongling. A model for linkage disequilibrium analysis in an autotetraploid natural population[J]. JOURNAL OF NANJING FORESTRY UNIVERSITY. 2014, 38(04): 29-33 https://doi.org/10.3969/j.issn.1000-2006.2014.04.006

References

[1] Grant V. Plant Speciation [M]. New York: Columbia University Press, 1981.
[2] Müntzing A. The evolutionary significance of autopolyploidy[J]. Hereditas, 1936, 21(2-3): 363-378.
[3] Darlington C D. Chromosome behaviour and structural hybridity in the tradescantiae: Ⅱ[J]. Journal of Genetics, 1937, 35(2): 259-280.
[4] 乔传卓,吴美枢,戴富宝,等. 菘蓝多倍体育种的研究 [J]. 植物学报,1989,31(9):678-683.Qiao C Z, Wu M S, Dai F B, et al. Studies on polyploidy breeding of Isatis indigotica Fort.[J]. Acta Botanica Sinica, 1989,31(9): 678-683.
[5] 丁如贤,郑水庆,邢爱婷,等. 决明多倍体的诱导与鉴定[J]. 中草药,2007,38(2):1090-1092.
[6] 彭云霞,王宏霞,李玉萍. 植物多倍体研究综述[J]. 甘肃农业科技,2012(11):29-32.Peng Y X, Wang H X, Li Y P. The research summary of plant polyploidy[J]. Gansu Agr Sci and Techn, 2012(11):29-32.
[7] Soltis P S, Soltis D E. The role of genetic and genomic attributes in the success of polyploids[J]. Proceedings of the National Academy of Sciences, 2000, 97(13): 7051-7057.
[8] Abdurakhmonov I Y, Kohel R J, Yu J Z, et al. Molecular diversity and association mapping of fiber quality traits in exotic G. hirsutum L. germplasm[J]. Genomics, 2008, 92(6): 478-487.
[9] Jorde L B. Linkage disequilibrium and the search for complex disease genes[J]. Genome research, 2000, 10(10): 1435-1444.
[10] Mackay I, Powell W. Methods for linkage disequilibrium mapping in crops[J]. Trends in Plant Science, 2007, 12(2): 57-63.
[11] Abdurakhmonov I Y, Saha S, Jenkins J N, et al. Linkage disequilibrium based association mapping of fiber quality traits in G. hirsutum L. variety germplasm[J]. Genetica, 2009, 136(3): 401-417.
[12] 杨小红,严建兵,郑艳萍,等.植物数量性状关联分析研究进展[J]. 作物学报,2007,33(4):523-530.Yang X H, Yan J B, Zheng Y P, et al. Reviews of association analysis for quantitative traits in plants[J]. Acta Agronomica Sinica, 2007, 33(4):523-530.
[13] Fisher R A. The theory of linkage in polysomic inheritance[J]. Philosophical Transactions of the Royal Society of London: Series B, Biological Sciences, 1947, 233(594): 55-87.
[14] Wu R, Gallo-Meagher M, Littell R C, et al. A general polyploid model for analyzing gene segregation in outcrossing tetraploid species[J]. Genetics, 2001, 159(2): 869-882.
[15] Julier B. A program to test linkage disequilibrium between loci in autotetraploid species[J]. Molecular Ecology Resources, 2009, 9(3): 746-748.
[16] Kremer A, Caron H, Cavers S, et al. Monitoring genetic diversity in tropical trees with multilocus dominant markers[J]. Heredity, 2005, 95(4): 274-280.
[17] Stephens J C, Schneider J A, Tanguay D A, et al. Haplotype variation and linkage disequilibrium in 313 human genes[J]. Science, 2001, 293(5529): 489-493.
[18] Ardlie K G, Kruglyak L, Seielstad M. Patterns of linkage disequilibrium in the human genome[J]. Nature Reviews Genetics, 2002, 3(4): 299-309.
[19] Dawson E, Abecasis G R, Bumpstead S, et al. A first-generation linkage disequilibrium map of human chromosome 22[J]. Nature, 2002, 418(6897): 544-548.
[20] Lynch M, Walsh B. Genetics and Analysis of Quantitative Traits[Z]. Sunderland MA:.Sinauer Associates, 1998.
[21] Rafalski A, Morgante M. Corn and humans: recombination and linkage disequilibrium in two genomes of similar size[J]. Trends in Genetics, 2004, 20(2): 103-111.
[22] Gabriel S B, Schaffner S F, Nguyen H, et al. The structure of haplotype blocks in the human genome[J]. Science, 2002, 296(5576): 2225-2229.
[23] Tishkoff S A, Williams S M. Genetic analysis of African populations: human evolution and complex disease[J]. Nature Reviews Genetics, 2002, 3(8): 611-621.
PDF(1388885 KB)

Accesses

Citation

Detail

Sections
Recommended
The full text is translated into English by AI, aiming to facilitate reading and comprehension. The core content is subject to the explanation in Chinese.

/