JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2014, Vol. 38 ›› Issue (04): 29-33.doi: 10.3969/j.issn.1000-2006.2014.04.006

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A model for linkage disequilibrium analysis in an autotetraploid natural population

FENG Sisi1, WANG Jianxin1,2, PANG Xiaoming1, WU Rongling1*   

  1. 1.Center for Computational Biology, Beijing Forestry University, Beijing 100083,China;
    2. School of Information Science &
    Technology, Beijing Forestry University,Beijing 100083,China
  • Online:2014-07-31 Published:2014-07-31

Abstract: More than 50% of angiosperms are polyploidy, or have experienced genome doubling in their evolutionary history. Thus, polyploids provide a valuable tool to study the genetics and evolution of plants. Linkage disequilibrium analysis has been widely used to infer the genetic structure, differentiation and diversity of natural populations, but its basic principle was found on a diploid population. In this article, we have derived a model for linkage disequilibrium analysis between a pair of molecular markers for the first time based on meiotic properties of autotetraploids. Computer simulation has been performed to examine the usefulness of the new model and determine the condition of its utilization.

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