[1] SELVI B.Comparative study of Pentanema verbascifolium extracts: Phytochemical composition, antioxidant potential, and enzyme inhibition across plant parts[J]. Food Bioscience, 2025, 68: 106607. DOI:10.1016/j.fbio.2025.106607.
[2] BAI Z Z, TANG J M, LI Y J, et al.Integrated metabolomics approach reveals the dynamic variations of metabolites and bioactivities in Paeonia ostii 'Feng Dan' leaves during development[J]. International Journal of Molecular Sciences, 2024, 25(2): 1059. DOI:10.3390/ijms25021059.
[3] HOU J Q, ZHOU Y H, RAN L P, et al.Transcriptome and metabolome analysis reveal the flavonoid biosynthesis mechanism of Abelmoschus manihot L. at different anthesis stages[J]. Metabolites, 2023, 13(2): 216. DOI:10.3390/metabo13020216.
[4] SANG X T, ZHEN F, LV P, et al.Green and chemical-free pretreatment of flavonoids in tea plant seed husk using ultrasound-cold isostatic pressure synergistic extraction[J]. Food Chemistry, 2025, 478: 143725. DOI:10.1016/j.foodchem.2025.143725.
[5] FERREYRA M L F, RIUS S P, CASATI P. Flavonoids: biosynthesis, biological functions, and biotechnological applications[J]. Frontiers in Plant Science, 2012, 3: 222. DOI:10.3389/fpls.2012.00222.
[6] SHARMA A, SHAHZAD B, REHMAN A, et al.Response of phenylpropanoid pathway and the role of polyphenols in plants under abiotic stress[J]. Molecules, 2019, 24(13): 2452. DOI:10.3390/molecules24132452.
[7] KUMAR P, KUMAR D, PAL S, et al.Plant secondary metabolites in defense against phytopathogens: Mechanisms, biosynthesis, and applications[J]. Physiological and Molecular Plant Pathology, 2025, 138: 102639. DOI:10.1016/j.pmpp.2025.102639.
[8] ISAH T.Stress and defense responses in plant secondary metabolites production[J]. Biological Research, 2019, 52: 39. DOI:10.1186/s40659-019-0246-3.
[9] MACKON E, MACKON G C J D E, GUO Y Q, et al. Development and application of CRISPR/Cas9 to improve anthocyanin pigmentation in plants: Opportunities and perspectives[J]. Plant Science, 2023, 333: 111746. DOI:10.1016/j.plantsci.2023.111746.
[10] SELMA S, SANMARTIN N, ESPINOSA-RUIZ A, et al.Custom-made design of metabolite composition in N. benthamiana leaves using CRISPR activators[J]. Plant Biotechnology Journal, 2022, 20(8): 1578-1590. DOI:10.1111/pbi.13834.
[11] LIU W X, FENG Y, YU S H, et al.The flavonoid biosynthesis network in plants[J]. International Journal of Molecular Sciences, 2021, 22(23): 12824. DOI:10.3390/ijms222312824.
[12] 李源佳, 龚剑峰, 李彬, 等. 银杏黄酮类化合物生物合成与代谢调控研究进展[J]. 中国中药杂志,2025, 50(15): 4201-4208. LI Y J, GONG J F, LI B, et al. Research progress on biosynthesis and metabolic regulation of Ginkgo biloba flavonoids[J]. China Journal of Chinese Materia Medica, 2025, 50(15): 4201-4208. DOI:10.19540/j.cnki.cjcmm.20250510.201.
[13] MAO Y Y, LUO J J, CAI Z P.Biosynthesis and regulatory mechanisms of plant flavonoids: A review[J]. Plants-Basel, 2025, 14(12): 1847. DOI:10.3390/plants14121847.
[14] YIN X J, WANG T T, ZHANG M, et al.Role of core structural genes for flavonoid biosynthesis and transcriptional factors in flower color of plants[J]. Biotechnology & Biotechnological Equipment, 2021, 35(1): 1214-1229. DOI:10.1080/13102818.2021.1960605.
[15] XIAO H X, ZHANG D L, LI J Y, et al.The molecular basis underlying phenotypic diversity in Camellia flower coloration and the evolution of research paradigms[J]. Scientia Horticulturae, 2025, 353: 114474. DOI:10.1016/j.scienta.2025.114474.
[16] 葛诗蓓, 张学宁, 韩文炎, 等. 植物类黄酮的生物合成及其抗逆作用机制研究进展[J]. 园艺学报,2023, 50(1): 209-224. GE S B, ZHANG X N, HAN W Y, et al. Research progress on plant flavonoids biosynthesis and their anti-stress mechanism[J]. Acta Horticulturae Sinica, 2023, 50(1): 209-224. DOI:10.16420/j.issn.0513-353x.2021-1186.
[17] ZHUANG W B, LI Y H, SHU X C, et al.The classification, molecular structure and biological biosynthesis of flavonoids, and their roles in biotic and abiotic stresses[J]. Molecules, 2023, 28(8): 3599. DOI:10.3390/molecules28083599.
[18] SHEN N, WANG T F, GAN Q, et al.Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity[J]. Food Chemistry, 2022, 383: 132531. DOI:10.1016/j.foodchem.2022.132531.
[19] ZHOU Y H, XU X D, CHEN Y Z, et al.Combined metabolome and transcriptome analyses reveal the flavonoids changes and biosynthesis mechanisms in different organs of Hibiseu manihot L.[J]. Frontiers in Plant Science, 2022, 13: 817378. DOI:10.3389/fpls.2022.817378.
[20] WANG X, ZHANG J J, LIU Z G, et al.Comparative transcriptome analysis of three chrysanthemums provides insights into flavonoid and terpenoid biosynthesis[J]. Journal of Plant Biology, 2021, 64(5): 389-401. DOI:10.1007/s12374-021-09304-7.
[21] WU K X, LIU Y, LIU J, et al.Comparison of seasonally adaptive metabolic response strategies of two Acer species[J]. Forests, 2022, 13(12): 2141. DOI:10.3390/f13122141.
[22] 陈晓涓, 王海菊, 王富敏, 等. 基于WGCNA鉴定全缘叶绿绒蒿类黄酮合成途径关键基因[J]. 中国农业科学, 2024, 57(15): 3053-3070. CHEN X J, WANG H J, WANG F M, et al. Identification of key genes in the flavonoid synthesis pathway of Meconopsis integrifolia based on WGCNA[J]. Scientia Agricultura Sinica, 2024, 57(15): 3053-3070. DOI:10.3864/j.issn.0578-1752.2024.15.011.
[23] YU Y, XIE Z M, ZHU S F, et al.Multi-omics profiling reveals organ-specific anti-inflammatory metabolites and biosynthetic regulation in Lindera aggregata taproot-bark[J]. Industrial Crops and Products, 2025, 238: 122414. DOI:10.1016/j.indcrop.2025.122414.
[24] LU Z G, BAO H Y, REN S X, et al.Plant responses to UV-B radiation: physiology, transcription, epigenetics, and secondary metabolism[J]. Plant Physiology and Biochemistry, 2026, 234: 111309. DOI:10.1016/j.plaphy.2026.111309.
[25] LUO X N, SUN D Y, WANG S, et al.Integrating full-length transcriptomics and metabolomics reveals the regulatory mechanisms underlying yellow pigmentation in tree peony (Paeonia suffruticosa Andr.) flowers[J]. Horticulture Research, 2021, 8(1): 235. DOI:10.1038/s41438-021-00666-0.
[26] MARTENS S, PREUSS A, MATERN U.Multifunctional flavonoid dioxygenases: Flavonol and anthocyanin biosynthesis in Arabidopsis thaliana L.[J]. Phytochemistry, 2010, 71(10): 1040-1049. DOI:10.1016/j.phytochem.2010.04.016.
[27] 王江昱, 田淑婷, 张涵, 等. 单子叶观赏植物花青素苷呈色机制研究进展[J]. 扬州大学学报(农业与生命科学版), 2022, 43(5): 101-114. WANG J Y, TIAN S T, ZHANG H, et al. Coloring mechanism of anthocyanin in monocot ornamental plants[J]. Journal of Yangzhou University (Agricultural and Life Science Edition), 2022, 43(5): 101-114. DOI:10.16872/j.cnki.1671-4652.2022.05.012.
[28] XU L L, WANG X P.A comprehensive review of phenolic compounds in horticultural plants[J]. International Journal of Molecular Sciences, 2025, 26(12): 5767. DOI:10.3390/ijms26125767.
[29] QIN Q, TATSUZAWA F, NAKANE T, et al.Anthocyanins and Flavonols from the Flowers of Ranunculus Cultivars (Ranunculaceae) and Their Color Expression[J]. Horticulture Journal, 2024, 93(2): 114-125. DOI:10.2503/hortj.QH-098.
[30] CHAVES-SILVA S, DOS SANTOS A L, CHALFUN A, et al. Understanding the genetic regulation of anthocyanin biosynthesis in plants - Tools for breeding purple varieties of fruits and vegetables[J]. Phytochemistry, 2018, 153: 11-27. DOI:10.1016/j.phytochem.2018.05.013.
[31] LIM S H, YOU M K, KIM D H, et al.RNAi-mediated suppression of dihydroflavonol 4-reductase in tobacco allows fine-tuning of flower color and flux through the flavonoid biosynthetic pathway[J]. Plant Physiology and Biochemistry, 2016, 109: 482-490. DOI:10.1016/j.plaphy.2016.10.028.
[32] NUTRICATI E, SABELLA E, NEGRO C, et al.Anthocyanins and anthocyanin biosynthesis gene expression in Passiflora flower corona filaments[J]. Plants-Basel, 2025, 14(7): 1050. DOI:10.3390/plants14071050.
[33] SUN Y, HU P L, JIANG Y N, et al.Comprehensive analysis of metabolomics and transcriptomics reveals varied tepal pigmentation across Gloriosa varieties[J]. BMC Plant Biology, 2025, 25(1): 66. DOI:10.1186/s12870-025-06067-y.
[34] YUAN S X, QI H, YANG S N, et al.Role of delphinidin-3-glucoside in the sepal blue color change among Hydrangea macrophylla cultivars[J]. Scientia Horticulturae, 2023, 313: 111902. DOI:10.1016/j.scienta.2023.111902.
[35] XU J P, SHIN J Y, PARK P M, et al.Flower color modification through co-overexpression of the VtF3′5′H and RhNHX genes in Rosa hybrida[J]. Plant Cell Tissue and Organ Culture, 2023, 153(2): 403-416. DOI:10.1007/s11240-023-02480-z.
[36] NODA N, YOSHIOKA S, KISHIMOTO S, et al.Generation of blue chrysanthemums by anthocyanin B-ring hydroxylation and glucosylation and its coloration mechanism[J]. Science Advances, 2017, 3(7): e1602785. DOI:10.1126/sciadv.1602785.
[37] 曹运琳, 邢梦云, 徐昌杰, 等. 植物黄酮醇生物合成及其调控研究进展[J]. 园艺学报, 2018, 45(1): 177-192. CAO Y L, XING M Y, XU C J, et al. Biosynthesis of flavonol and its regulation in plants[J]. Acta Horticulturae Sinica, 2018, 45(1): 177-192. DOI:10.16420/j.issn.0513-353x.2017-0306.
[38] WANG Y, LU C, ZOU S H, et al.Integrated transcriptomic and metabolomic analyses of the molecular mechanisms of flower color variation in three Camellia species[J]. Plant Growth Regulation, 2025, 105(4): 1251-1273. DOI:10.1007/s10725-025-01335-1.
[39] XING A S, WANG X Y, NAZIR M F, et al.Transcriptomic and metabolomic profiling of flavonoid biosynthesis provides novel insights into petals coloration in Asian cotton (Gossypium arboreum L.)[J]. BMC Plant Biology, 2022, 22(1): 416. DOI:10.1186/s12870-022-03800-9.
[40] AI Y, ZHENG Q D, WANG M J, et al.Molecular mechanism of different flower color formation of Cymbidium ensifolium[J]. Plant Molecular Biology, 2023, 113(4-5): 193-204. DOI:10.1007/s11103-023-01382-0.
[41] LIU Q Q, ZHANG D S, LIU F L, et al.Quercetin-derivatives painting the yellow petals of American lotus (Nelumbo lutea) and enzymatic basis for their accumulation[J]. Horticultural Plant Journal, 2023, 9(1): 169-182. DOI:10.1016/j.hpj.2022.02.001.
[42] WANG J D, ZHAO Y Q, SUN B, et al.The structure of anthocyanins and the copigmentation by common micromolecular copigments: A review[J]. Food Research International, 2024, 176: 113837. DOI:10.1016/j.foodres.2023.113837.
[43] HUYEN D T T, URESHINO K, VAN D T, et al. Co-pigmentation of anthocyanin-flavonol in the blotch area of Rhododendron simsii Planch. flowers[J]. Horticulture Journal, 2016, 85(3): 232-237. DOI:10.2503/hortj.MI-092.
[44] LUO P, NING G G, WANG Z, et al.Disequilibrium of Flavonol Synthase and Dihydroflavonol-4-Reductase Expression Associated Tightly to White vs. Red Color Flower Formation in Plants[J]. Frontiers in Plant Science, 2016, 6: 1257. DOI:10.3389/fpls.2015.01257.
[45] CHOUDHARY N, PUCKER B.Conserved amino acid residues and gene expression patterns associated with the substrate preferences of the competing enzymes FLS and DFR[J]. PLOS ONE, 2024, 19(8): e0305837. DOI:10.1371/journal.pone.0305837.
[46] LUO X N, HUANG S J, JIANG F J, et al.Interaction of PsMYB4 with PsEGL3 inhibits anthocyanin biosynthesis in tree peony yellow flowers[J]. Frontiers in Plant Science, 2025, 16: 1595014. DOI:10.3389/fpls.2025.1595014.
[47] JOHNSON E T, RYU S, YI H K, et al.Alteration of a single amino acid changes the substrate specificity of dihydroflavonol 4-reductase[J]. Plant Journal, 2001, 25(3): 325-333. DOI:10.1046/j.1365-313x.2001.00962.x.
[48] CHUA C S, BIERMANN D, GOO K S, et al.Elucidation of active site residues of Arabidopsis thaliana flavonol synthase provides a molecular platform for engineering flavonols[J]. Phytochemistry, 2008, 69(1): 66-75. DOI:10.1016/j.phytochem.2007.07.006.
[49] ZHANG W H, ZHANG N Y, QIN Q, et al.RmMYB44 confers resistance to chilling, drought, and salt stress in both Rosa multiflora and tobacco[J]. Agriculture-Basel, 2024, 14(8): 1212. DOI:10.3390/agriculture14081212.
[50] ALI A, SANTORO P, MORI J, et al.Effect of UV-B elicitation on spearmint's (Mentha spicata L.) morpho-physiological traits and secondary metabolites production[J]. Plant Growth Regulation, 2024, 104(1): 63-76. DOI:10.1007/s10725-023-01028-7.
[51] LIN L J, LIN H T, ZHENG S J, et al.Metabolisms of ROS and membrane lipid participate in Pestalotiopsis microspora-induced disease occurrence of harvested Chinese olives[J]. Postharvest Biology and Technology, 2024, 210: 112720. DOI:10.1016/j.postharvbio.2023.112720.
[52] CANNEA F B, PADIGLIA A.Antioxidant defense systems in plants: mechanisms, regulation, and biotechnological strategies for enhanced oxidative stress tolerance[J]. Life-Basel, 2025, 15(8): 1293. DOI:10.3390/life15081293.
[53] NADARAJAH K K.ROS homeostasis in abiotic stress tolerance in plants[J]. International Journal of Molecular Sciences, 2020, 21(15): 5208. DOI:10.3390/ijms21155208.
[54] 张悦婧, 桑鹤天, 王涵琦, 等. 植物对非生物胁迫系统性反应中信号传递的研究进展[J]. 植物学报, 2024, 59(1): 122-133. ZHANG Y J, SANG H T, WANG H Q, et al. Research progress on signal transmission in systemic response of plants to abiotic stress[J]. Chinese Bulletin of Botany, 2024, 59(1): 122-133. DOI:10.11983/CBB23063.
[55] DONG W F, XIE Q J, LI J X, et al.BpMAPK3-mediated BpWRKY53 phosphorylation enhances Betula platyphylla drought stress tolerance by increasing flavonoid content[J]. Plant Journal, 2025, 121(6): e70089. DOI:10.1111/tpj.70089.
[56] LIN R, ZHANG W J, TIAN R, et al.CPK27 enhances cold tolerance by promoting flavonoid biosynthesis through phosphorylating HY5 in tomato[J]. New Phytologist, 2025, 246(5): 2174-2191. DOI:10.1111/nph.70134.
[57] ZHUANG Q Q, CHEN S P, JUA Z X, YAO Y.Joint transcriptomic and metabolomic analysis reveals the mechanism of low-temperature tolerance in Hosta ventricosa[J]. PLOS ONE, 2021, 16(11): e0259455. DOI:10.1371/journal.pone.0259455.
[58] WU D, WU Y X, GAO R Q, et al.Integrated metabolomics and transcriptomics reveal the key role of flavonoids in the cold tolerance of chrysanthemum[J]. International Journal of Molecular Sciences, 2024, 25(14): 7589. DOI:10.3390/ijms25147589.
[59] ZHANG M, LI M X, FU H W, et al.Transcriptomic analysis unravels the molecular response of Lonicera japonica leaves to chilling stress[J]. Frontiers in Plant Science, 2022, 13: 1092857. DOI:10.3389/fpls.2022.1092857.
[60] PENG Z, WANG Y, ZUO W T, et al.Integration of metabolome and transcriptome studies reveals flavonoids, abscisic acid, and nitric oxide comodulating the freezing tolerance in Liriope spicata[J]. Frontiers in Plant Science, 2022, 12: 764625. DOI:10.3389/fpls.2021.764625.
[61] 张亚平, 曾艳, 林雪莹, 等. 榉树叶色和色素组成的相互关系研究[J]. 河南农业科学, 2017, 46(6): 116-119. ZHANG Y P, ZENG Y, LIN X Y, et al. Correlation between leaf color and pigment composition of Zelkova schneideriana[J]. Journal of Henan Agricultural Sciences, 2017, 46(6): 116-119. DOI:10.15933/j.cnki.1004-3268.2017.06.022.
[62] 汤努尔·瓦力拜, 李厚华, 李果, 等. 不同叶色三叶海棠叶片成色色素分析[J]. 广西植物, 2017, 37(12): 1572-1578. WALIBAI T, LI H H, LI G, et al. Pigment analysis on different colors of leaves from Malus sieboldii[J]. Guihaia, 2017, 37(12): 1572-1578. DOI:10.11931/guihaia.gxzw201703039.
[63] GONG F S, MENG J H, XU H W, et al.The molecular mechanism regulating flavonoid production in Rhododendron chrysanthum Pall. against UV-B damage is mediated by RcTRP5[J]. International Journal of Molecular Sciences, 2024, 25(24): 13383. DOI:10.3390/ijms252413383.
[64] LIU S H, FANG S, LIU C L, et al.Transcriptomics integrated with metabolomics reveal the effects of ultraviolet-B radiation on flavonoid biosynthesis in Antarctic moss[J]. Frontiers in Plant Science, 2021, 12: 788377. DOI:10.3389/fpls.2021.788377.
[65] SHI C, LIU H T.How plants protect themselves from ultraviolet-B radiation stress[J]. Plant Physiology, 2021, 187(3): 1096-1103. DOI:10.1093/plphys/kiab245.
[66] LIU W, JENKINS G I.Recent advances in UV-B signalling: interaction of proteins with the UVR8 photoreceptor[J]. Journal of Experimental Botany, 2024, 76(3): 873-881. DOI:10.1093/jxb/erae132.
[67] YANG Y J, YANG X L, JANG Z F, et al.UV RESISTANCE LOCUS 8 From Chrysanthemum morifolium Ramat (CmUVR8) Plays Important Roles in UV-B Signal Transduction and UV-B-Induced Accumulation of Flavonoids[J]. Frontiers in Plant Science, 2018, 9: 955. DOI:10.3389/fpls.2018.00955.
[68] LIU S, GU X Y, JIANG Y B, et al. UV-B promotes flavonoid biosynthesis in Ginkgo biloba by inducing the GbHY5-GbMYB1-GbFLS module[J]. Horticulture Research, 2023, 10(8): uhad118. DOI:10.1093/hr/uhad118.
[69] LIANG Y E, ZHANG H, ZHU J H, et al.Transcriptomic analysis reveals the involvement of flavonoids synthesis genes and transcription factors in Dracaena cambodiana response to ultraviolet-B radiation[J]. Forests, 2023, 14(5): 979. DOI:10.3390/f14050979.
[70] KAISERLI E, JENKINS G I.UV-B promotes rapid nuclear translocation of the Arabidopsis UV-B-specific signaling component UVR8 and activates its function in the nucleus[J]. Plant Cell, 2007, 19(8): 2662-2673. DOI:10.1105/tpc.107.053330.
[71] FANG F, LIN L, ZHANG Q W, et al.Mechanisms of UV-B light-induced photoreceptor UVR8 nuclear localization dynamics[J]. New Phytologist, 2022, 236(5): 1824-1837. DOI:10.1111/nph.18468.
[72] TANG Z Q, WANG J H, LI R Z, et al.Expression analysis and functional study of honeysuckle MYB transcription factors under drought stress[J]. Scientific Reports, 2025, 15(1): 14843. DOI:10.1038/s41598-025-99946-1.
[73] SUN R, LIU S, GAO J L, et al.Integration of the metabolome and transcriptome reveals the molecular mechanism of drought tolerance in Plumeria rubra[J]. Frontiers in Genetics, 2023, 14: 1274732. DOI:10.3389/fgene.2023.1274732.
[74] WU Y Q, LI T T, CHENG Z Y, et al.R2R3-MYB transcription factor PlMYB108 confers drought tolerance in herbaceous peony (Paeonia lactiflora Pall.)[J]. International Journal of Molecular Sciences, 2021, 22(21): 11884. DOI:10.3390/ijms222111884.
[75] ZHAO C N, HOU H Y, WU J X, et al.DcMYB30 negatively function in drought tolerance of Dendrobium catenatum by modulating flavonoid biosynthesis[J]. Plant Physiology and Biochemistry, 2025, 227: 110199. DOI:10.1016/j.plaphy.2025.110199.
[76] LI W L, YU S M, ZHANG K M, et al.Characterization of the JAZ family in Osmanthus fragrans and the role of OfLJAZ2 in flavonoid synthesis mediated regulation of salt and drought stress tolerance[J]. Plant Physiology and Biochemistry, 2025, 228: 110235. DOI:10.1016/j.plaphy.2025.110235.
[77] DURIC M, SUBOTIC A, PROKIC L, et al.Foliar application of methyl jasmonate affects impatiens walleriana growth and leaf physiology under drought stress[J]. Plant Signaling & Behavior, 2023, 18(1): 2219936. DOI:10.1080/15592324.2023.2219936.
[78] DENG B, LI Y Y, XU D D, et al.Nitrogen availability alters flavonoid accumulation in Cyclocarya paliurus via the effects on the internal carbon/nitrogen balance[J]. Scientific Reports, 2019, 9: 2370. DOI:10.1038/s41598-019-38837-8.
[79] LI Z Y, JIANG H, YAN H Z A, et al. Carbon and nitrogen metabolism under nitrogen variation affects flavonoid accumulation in the leaves of Coreopsis tinctoria[J]. PeerJ, 2021, 9: e12152. DOI:10.7717/peerj.12152.
[80] WANG Q, DU B Q, BAI Y J, et al. Saline-alkali stress affects the accumulation of proanthocyanidins and sesquiterpenoids via the MYB5-ANR/TPS31 cascades in the rose petals[J]. Horticulture Research, 2024, 11(11): uhae243. DOI:10.1093/hr/uhae243.
[81] 王晚霞. 垂丝海棠MhANS与MhANR基因克隆与调控盐碱胁迫的功能鉴定[D]. 甘肃农业大学, 2023. WANG W X. Cloning of MhANS and MhANR genes and functional identification of regulating saline-alkali stress in Malus halliana[D]. Gansu Agricultural University, 2023. DOI:10.27025/d.cnki.ggsnu.2023.000135.
[82] NOUMAN W, GULL T, SHAHEEN M, GUL R.Hormesis management of Moringa oleifera with exogenous application of plant growth regulators under saline conditions[J]. International Journal of Phytoremediation, 2024, 26(6): 947-963. DOI:10.1080/15226514.2023.2285846.
[83] LIU Q W, CHEN S Y, WANG Y K, et al.Prunus persica (L.) Batsch root enriched Pseudomonas for enhanced saline-alkali tolerance by inducing fatty acid and flavonoid biosynthesis[J]. Plant Physiology and Biochemistry, 2026, 232: 111134. DOI:10.1016/j.plaphy.2026.111134.
[84] STROUD E A, JAYARAMAN J, TEMPLETON M D, et al.Comparison of the pathway structures influencing the temporal response of salicylate and jasmonate defence hormones in Arabidopsis thaliana[J]. Frontiers in Plant Science, 2022, 13: 952301. DOI:10.3389/fpls.2022.952301.
[85] ALI J, TONGA A, ISLAM T, et al.Defense strategies and associated phytohormonal regulation in Brassica plants in response to chewing and sap-sucking insects[J]. Frontiers in Plant Science, 2024, 15: 1376917. DOI:10.3389/fpls.2024.1376917.
[86] 焦龙, 陈勋, 谭荣荣, 等. 植物茉莉酸与水杨酸信号途径互作研究进展[J]. 植物生理学报, 2023, 59(8): 1489-1504. JIAO L, CHEN X, TAN R R, et al. Research progress on the interaction between jasmonic acid and salicylic acid signaling pathways in plants[J]. Plant Physiology Journal, 2023, 59(8): 1489-1504. DOI:10.13592/j.cnki.ppj.300133.
[87] BAI Q X, DUAN B B, MA J C, et al.Coexpression of PalbHLH1 and PalMYB90 genes from Populus alba enhances pathogen resistance in poplar by increasing the flavonoid content[J]. Frontiers in Plant Science, 2019, 10: 1772. DOI:10.3389/fpls.2019.01772.
[88] SHI X Q, WANG Y Z, GONG S, et al.The preliminary analysis of flavonoids in the petals of Rhododendron delavayi, Rhododendron agastum and Rhododendron irroratum infected with Neopestalotiopsis clavispora[J]. International Journal of Molecular Sciences, 2024, 25(17): 9605. DOI:10.3390/ijms25179605.
[89] WANG S Z, LI M J, WANG J Y, et al.Integrated multi-omics analysis revealed the response mechanism of Osmanthus fragrans leaves against the infection by Botryosphaeria dothidea[J]. Frontiers in Plant Science, 2026, 17: 1830904. DOI:10.3389/fpls.2026.1830904.
[90] ACEVEDO F E, SMITH P, PEIFFER M, et al.Phytohormones in fall armyworm saliva modulate defense responses in plants[J]. Journal of Chemical Ecology, 2019, 45(7): 598-609. DOI:10.1007/s10886-019-01079-z.
[91] SHINDE S, KUNDU P, SHRESTHA K, et al.Flavonoids at the crossroads of plant defence: a multifunctional shield against insect pests[J]. Journal of Experimental Botany, 2026, 77(10): 2815-2834. DOI:10.1093/jxb/erag096.
[92] PURI H, IKUZE E, AYALA J, et al.Greenbug feeding-induced resistance to sugarcane aphids in sorghum[J]. Frontiers in Ecology and Evolution, 2023, 11: 1105725. DOI:10.3389/fevo.2023.1105725.
[93] SHINDE S, KUNDU P, LOUIS J.Beyond bites: Differential role of fall armyworm oral secretions and saliva in modulating sorghum defenses[J]. Molecular Plant-Microbe Interactions, 2024, 37(3): 232-238. DOI:10.1094/MPMI-12-23-0213-FI.
[94] SCHOTT J, FUCHS B, BÖTTCHER C, et al. Responses to larval herbivory in the phenylpropanoid pathway of Ulmus minor are boosted by prior insect egg deposition[J]. Planta, 2022, 255(1): 16. DOI:10.1007/s00425-021-03803-0.
[95] WANG Y, ZHANG W W, HONG C J, et al.Chrysanthemum (Chrysanthemum morifolium) CmHRE2-like negatively regulates the resistance of chrysanthemum to the aphid (Macrosiphoniella sanborni)[J]. BMC Plant Biology, 2024, 24(1): 76. DOI:10.1186/s12870-024-04758-6.
[96] 曹雪瑶, 宋南黎, 张楚君, 等. 乌桕应对多种昆虫取食的次生代谢响应[J]. 应用昆虫学报, 2025, 62(3): 774-782. CAO X Y, SONG N L, ZHANG C J, et al. Secondary metabolic responses of Triadica sebifera to feeding by multiple herbivores[J]. Chinese Journal of Applied Entomology, 2025, 62(3): 774-782. DOI:10.7679/j.issn.2095-1353.2025.073.
[97] REN S X, CUI J W, WANG L, et al.Plant flavonoids: biosynthesis, regulation, and roles in biotic and abiotic stresses[J]. Plant Cell and Environment, 2026, DOI:10.1111/pce.70540.
[98] DÍAZ-GUERRA L, LLORENS L, JULKUNEN-TIITTO R, et al. Leaf biochemical adjustments in two Mediterranean resprouter species facing enhanced UV levels and reduced water availability before and after aerial biomass removal[J]. Plant Physiology and Biochemistry, 2019, 137: 130-143. DOI:10.1016/j.plaphy.2019.01.031.
[99] MA X, OU Y B, GAO Y F, et al.Moderate salt treatment alleviates ultraviolet-B radiation caused impairment in poplar plants[J]. Scientific Reports, 2016, 6: 32890. DOI:10.1038/srep32890.
[100] ZHAO Y, LIU G Z, YANG F, et al.Multilayered regulation of secondary metabolism in medicinal plants[J]. Molecular Horticulture, 2023, 3(1): 11. DOI:10.1186/s43897-023-00059-y.
[101] NAIK J, MISRA P, TRIVEDI P K, et al.Molecular components associated with the regulation of flavonoid biosynthesis[J]. Plant Science, 2022, 317: 111196. DOI:10.1016/j.plantsci.2022.111196.
[102] YANG F, WANG T, GUO Q S, et al.The CmMYB3 transcription factors isolated from the Chrysanthemum morifolium regulate flavonol biosynthesis in Arabidopsis thaliana[J]. Plant Cell Reports, 2023, 42(4): 791-803. DOI:10.1007/s00299-023-02991-1.
[103] SHEN Y X, SUN T T, PAN Q, et al.RrMYB5- and RrMYB10-regulated flavonoid biosynthesis plays a pivotal role in feedback loop responding to wounding and oxidation in Rosa rugosa[J]. Plant Biotechnology Journal, 2019, 17(11): 2078-2095. DOI:10.1111/pbi.13123.
[104] ANWAR M, WANG G Q, WU J C, et al.Ectopic overexpression of a novel R2R3-MYB, NtMYB2 from Chinese Narcissus represses anthocyanin biosynthesis in tobacco[J]. Molecules, 2018, 23(4): 781. DOI:10.3390/molecules23040781.
[105] ANWAR M, YU W J, YAO H, et al.NtMYB3, an R2R3-MYB from Narcissus, regulates flavonoid biosynthesis[J]. International Journal of Molecular Sciences, 2019, 20(21): 5456. DOI:10.3390/ijms20215456.
[106] BAUDRY A, CABOCHE M, LEPINIEC L.TT8 controls its own expression in a feedback regulation involving TTG1 and homologous MYB and bHLH factors, allowing a strong and cell-specific accumulation of flavonoids in Arabidopsis thaliana[J]. Plant Journal, 2006, 46(5): 768-779. DOI:10.1111/j.1365-313X.2006.02733.x.
[107] HUANG W J, SUN W, LV H Y, et al.A R2R3-MYB transcription factor from Epimedium sagittatum regulates the flavonoid biosynthetic pathway[J]. PLOS ONE, 2013, 8(8): e70778. DOI:10.1371/journal.pone.0070778.
[108] LIM S H, KIM D, JUNG J A, et al.Alternative splicing of the basic helix-loop-helix transcription factor gene CmbHLH2 affects anthocyanin biosynthesis in ray florets of chrysanthemum (Chrysanthemum morifolium)[J]. Frontiers in Plant Science, 2021, 12: 669315. DOI:10.3389/fpls.2021.669315.
[109] RAMSAY N A, GLOVER B J.MYB-bHLH-WD40 protein complex and the evolution of cellular diversity[J]. Trends in Plant Science, 2005, 10(2): 63-70. DOI:10.1016/j.tplants.2004.12.011.
[110] WANG Y T, TIAN H N, WANG W, et al.The carboxyl-terminus of TRANSPARENT TESTA GLABRA1 is critical for its functions in Arabidopsis[J]. International Journal of Molecular Sciences, 2021, 22(18): 10039. DOI:10.3390/ijms221810039.
[111] WEI Z L, CHENG Y L, ZHOU C C, et al.Genome-wide identification of direct targets of the TTG1-bHLH-MYB complex in regulating trichome formation and flavonoid accumulation in Arabidopsis thaliana[J]. International Journal of Molecular Sciences, 2019, 20(20): 5014. DOI:10.3390/ijms20205014.
[112] CHEN S Y, WANG S C.GLABRA2, a common regulator for epidermal cell fate determination and anthocyanin biosynthesis in Arabidopsis[J]. International Journal of Molecular Sciences, 2019, 20(20): 4997. DOI:10.3390/ijms20204997.
[113] GAO Y F, LIU J K, CHEN Y F, et al.Tomato SlAN11 regulates flavonoid biosynthesis and seed dormancy by interaction with bHLH proteins but not with MYB proteins[J]. Horticulture Research, 2018, 5: 27. DOI:10.1038/s41438-018-0032-3.
[114] ZHU L, GUAN Y X, ZHANG Z H, et al.CmMYB8 encodes an R2R3 MYB transcription factor which represses lignin and flavonoid synthesis in chrysanthemum[J]. Plant Physiology and Biochemistry, 2020, 149: 217-224. DOI:10.1016/j.plaphy.2020.02.010.
[115] LUO J Y, LUO C, HAN M Z, et al.A natural variation of flavone synthase II gene enhances flavone accumulation and confers drought adaptation in chrysanthemum[J]. New Phytologist, 2025, 247(3): 1445-1459. DOI:10.1111/nph.70255.
[116] LIM S H, KIM D, JUNG J A, et al.Silencing of dihydroflavonol 4-reductase in chrysanthemum ray florets enhances flavonoid biosynthesis and antioxidant capacity[J]. Plants, 2022, 11(13): 1681. DOI:10.3390/plants11131681.
[117] LIU H T, WANG Z Z, LIU Y, et al.Applications of CRISPR/Cas9 technology in ornamental plants[J]. Plant Molecular Biology Reporter, 2024, 42(2): 193-200. DOI:10.1007/s11105-023-01417-2.
[118] NITARSKA D, BOEHM R, DEBENER T, et al.First genome edited poinsettias: targeted mutagenesis of flavonoid 3′-hydroxylase using CRISPR/Cas9 results in a colour shift[J]. Plant Cell Tissue and Organ Culture, 2021, 147(1): 49-60. DOI:10.1007/s11240-021-02103-5.
[119] TASAKI K, HIGUCHI A, WATANABE A, et al.Effects of knocking out three anthocyanin modification genes on the blue pigmentation of gentian flowers[J]. Scientific Reports, 2019, 9: 15831. DOI:10.1038/s41598-019-51808-3.
[120] SHIH M L, MORGAN J A.Metabolic flux analysis of secondary metabolism in plants[J]. Metabolic Engineering Communications, 2020, 10: e00123. DOI:10.1016/j.mec.2020.e00123.
[121] DONG Y H, FELDBERG L, ROGACHEV I, et al.Characterization of the PRODUCTION of ANTHOCYANIN PIGMENT 1 Arabidopsis dominant mutant using DLEMMA dual isotope labeling approach[J]. Phytochemistry, 2021, 186: 112740. DOI:10.1016/j.phytochem.2021.112740.