JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2014, Vol. 38 ›› Issue (02): 161-164.doi: 10.3969/j.issn.1000-2006.2014.02.031

Previous Articles     Next Articles

Synthesis of triazole compounds and evaluation of their antimicrobial activities

YAN Lele1 ,LIU Xingping1*,CHENG Kanghua2,LI Jing1   

  1. 1.College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210046,China;
    2.College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037,China
  • Online:2014-03-10 Published:2014-03-10

Abstract: In order to get a wood preservative with higher efficiency, six compounds Y-4(a-f)were synthesized using 1, 3-dichlorobenzene as the starting material by Friedel-crafts acetylation, alkylation, epoxidation, and ring-opening reaction. The structures of these compounds were determined by MS and 1H-NMR. Antifungal activities of these compounds were evaluated by two moulds and two decay fungi with Filter paper diffusion. The results indicated that Y-4d had a broad spectrum of antibacteria on moulds and decay fungi, but Y-4c and Y-4f had better antibacterial effect on decay fungi.

CLC Number: