A novel QTL mapping model for allometric growth and pleiotropic extension

doi:10.3969/j.issn.1000-2006.2014.03.007

JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2014, Vol. 38 ›› Issue (03): 35-39.doi: 10.3969/j.issn.1000-2006.2014.03.007

Previous Articles Next Articles

A novel QTL mapping model for allometric growth and pleiotropic extension

LI Jie¹,WANG Zhong^2*,LI Yongci^3*,GAI Junyi⁴,HUANG Zhongwen⁵,WU Rongling²

1. College of Forestry,Beijing Forestry University,Beijing 100083,China;
2. College of Biology,Beijing Forestry University,Beijing 100083, China;
3. College of Science,Beijing Forestry University,Beijing 100083,China;
4.College of Agronomy,Nanjing Agricultural University,Nanjing 210095,China;
5. Department of Agronomy,Henan Institute of Science and Technology,Xinxiang 453003,China

Online:2014-05-15 Published:2014-05-15

Abstract

Abstract: Allometric growth has been widely studied as an important law in biology. In order to reveal allometric growth and its pleiotropism, a new model is proposed to map the QTL which is related to allometric growth based on the framework of functional mapping in this paper. Using this model, a soybean population of recombinant inbred lines(RIL)is demonstrated to analyze the QTLs which affect allometric growth between leaf biomass and total weight. The QTLs in the 24th linkage groups detected by this model are testified by the Logistic model to find out pleiotropism. This extended model improves the accuracy of QTL mapping and estimate of the parameters of allometric growth by means of two merits, which the dynamic traits of biological growth processes are conceived and multiple time points in the experimental data are employed.

CLC Number:

S722

LI Jie,WANG Zhong,LI Yongci,GAI Junyi,HUANG Zhongwen,WU Rongling. A novel QTL mapping model for allometric growth and pleiotropic extension[J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2014, 38(03): 35-39.

References

[1] Lander E S, Botstein D. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps [J]. Genetics, 1989, 121(1):185-199.
[2] Zeng Z B. Precision mapping of quantitative trait loci [J]. Genetics, 1994, 136(4):1457-1468.
[3] Wu R L, Ma C X, Casella G. Joint linkage and linkage disequilibrium mapping of quantitative trait loci in natural populations [J]. Genetics, 2002, 160(2):779-792.
[4] Zou F, Nie L, Wright F A, et al. A robust QTL mapping procedure [J]. Journal of Statistical Planning and Inference, 2009, 139(3):978-989.
[5] 童春发, 施季森. 回归法QTL作图效率的分析[J]. 南京林业大学学报:自然科学版, 2001, 25(4):12-16. Tong C F, Shi J S. Effects analysis using regression method for mapping QTL[J]. Journal of Nanjing University:Natural Sciences Edition, 2001, 25(4):12-16.
[6] 童春发. 林木遗传图谱构建和QTL定位的统计方法[J]. 南京林业大学学报:自然科学版, 2004, 28(1):109-114. Tong C F. Statistical methods for constructing genetic linkage maps and mapping QTLs in forest trees[J]. Journal of Nanjing University: Natural Sciences Edition, 2004, 28(1):109-114.
[7] Frary A, Nesbitt T C, Frary A, et al. fw2.2: a quantitative trait locus key to the evolution of tomato fruit size[J]. Science, 2000, 289(5476): 85-88.
[8] Li C, Zhou A, Sang T. Rice domestication by reducing shattering [J]. Science, 2006, 311(5769):1936-1939.
[9] Huang X, Qian Q, Liu Z, et al. Natural variation at the DEP1 locus enhances grain yield in rice [J]. Nature Genetics, 2009, 41(4):494-497.
[10] Ma C X, Casella G, Wu R L. Functional mapping of quantitative trait loci underlying the character process: A theoretical framework[J]. Genetics, 2002,161(4):1751-1762.
[11] Wu R L, Lin M. Functional mapping-how to map and study the genetic architecture of dynamic complex traits [J]. Nature Reviews Genetics, 2006, 7(3):229-237.
[12] West G B, Brown J H, Enquist B J. A general model for the origin of allometric scaling laws in biology [J]. Science, 1997, 276(5309):122-126.
[13] Ma C X, Casella G, Littell R C,et al. Exponential mapping of quantitative trait loci governing allometric relationships in organisms [J]. Journal of Mathematical Biology, 2003, 47(4): 313-324.
[14] Long F, Chen Y Q, Cheverud J M, et al. Genetic mapping of allometric scaling laws [J]. Genetical Research, 2006, 87(3):207-216.
[15] Li H Y, Huang Z W, Gai J Y, et al. A conceptual framework for mapping quantitative trait loci regulating ontogenetic allometry [J]. PLoS One, 2007, 2(11): 1245.
[16] Thomas Baeck, Fogel David B, Zbigniew Michalewicz. Evolutionary Computation 1:Basic Algorithms and Operators [M]. New York:Taylor and Francis Group, 2000.
[17] Zhao W, Chen Y Q, Casella G, et al. A non-stationary model for functional mapping of complex traits [J]. Bioinformatics, 2005, 21(10):2469-2477.
[18] Wu R L, Ma C X, Casella G. Statistical Genetics of Quantitative traits: Linkage, Maps, and QTL [M]. New York: Springer-Verlag, 2007.
[19] Beale E M L. Cycling in the dual simplex algorithm[J]. Naval Research Logistics Quarterly, 1955, 2(5):269-276.
[20] John D Head, Michael C Zerner. A Broyden-Fletcher-Goldfarb-Shanno optimization procedure for molecular geometries[J]. Chemical Physics Letters, 1985, 122(3):264-270.
[21] Zhang W K, Wang Y J, Luo G Z, et al. QTL mapping of ten agronomic traits on the soybean(Glycine max L. Merr.)genetic map and their association with EST makers[J]. Theor Appl Genet, 2004, 108(6):1131-1139.
[22] Glazier D S. Beyond the ‘3/4-power law’ variation in the intra-and interspecific scaling of metabolic rate in animals [J]. Biological Reviews, 2005, 80(4):611-662.
[23] Klingenberg C P. Heterochrony and allometry: the analysis of evolutionary change in ontogeny [J]. Biological Reviews, 1998, 73(1):79-123.

Related Articles 15

[1]	XU Huihui, BAN Zhuo, WANG Chenxue, BI Quanxin, LIU Xiaojuan, WANG Libing. The identification and functional analysis of BZR1 genes in yellowhorn [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(2): 12-22.
[2]	QI Ya, WANG Gaiping, XUANYUAN Xintong, PENG Daqing, LI Shuomin, LI Shouke, CAO Fuliang. Evaluation of medicinal asexual strains of Xanthoceras sorbifolium [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(2): 38-44.
[3]	CHEN Shengkan, GUO Dongqiang, DENG Ziyu, TANG Qinglan, LIAO Changkun, YANG Zhiwang, ZHU Yuanli, LI Changrong. Stability evaluation on tree height for introduced provenances of Corymbia citriodora subsp. variegata [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(2): 67-74.
[4]	YAO Junxiu, REN Fei, WANG Yinhua, LI Qinghua, YAN Liping, ZHENG Yan, WU Dejun. Genetic diversity of germplasm resources of Sambucus based on SSR fluorescent marker [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(2): 75-82.
[5]	KE Xin, FEI Qi, XIA Xinrui, YE Jianren, ZHU Lihua. The factors influencing the embryogenic callus initiation and somatic embryo yield in Pinus elliottii resistant to pine needle brown spot disease [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(1): 87-94.
[6]	LIN Qiang, XU Jin, LI Shangqian, LIN Yunbin, ZHANG Yunqing, OUYANG Lei. The early selection and analysis of genetic variation of Cryptomeria japonica half-sib progeny from seed orchard in Fuding, Fujian Province [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(1): 78-86.
[7]	JIANG Bo, AN Xinmin. Precise genomic editing technology and its application in the improvement of woody plants [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(1): 11-20.
[8]	ZHANG Weixi, DING Mi, SU Xiaohua, LI Aiping, WANG Xiaojiang, YU Jinjin, LI Zhenghong, HUANG Qinjun, DING Changjun. Heterosis and drought resistance assessment of Populus simonii × P. nigra F₁ hybrids based on growth traits and leaf anatomical structures [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2025, 49(1): 46-58.
[9]	YANG Yuanmu, LI Na, CHEN Xinyu, XU Fang, PAN Wen, ZHANG Weihua. Study on wood variation of provenances and clones of Castanopsis hystrix [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2024, 48(6): 41-50.
[10]	YAN Pingyu, ZHANG Lei, WANG Jiaxing, FENG Kele, WANG Haohao, ZHANG Hanguo. Analysis of genetic diversity and construction of core collections of Korean pine (Pinus koraiensis) natural population [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2024, 48(5): 69-80.
[11]	WANG Jiaxing, YAN Pingyu, SUN Baifei, LIU Jinhong, FENG Kele, ZHANG Hanguo. Growth variation and superior families early selection of Larix olgensis free-pollinated families [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2024, 48(5): 81-89.
[12]	KUANG Zeyu, PENG Ye, FANG Yanming. Effects of volatile organic components of Ilex rotunda on its insect pollinator, Apis cerana [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2024, 48(4): 254-260.
[13]	LIU Li, QU Yinquan, YU Yanhao, WANG Qian, FU Xiangxiang. Analysis of SSR locus based on the whole genome sequences of Cyclocarya paliurus and the development of polymorphic primers [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2024, 48(4): 67-75.
[14]	LIU Xialan, SONG Ziqi, HU Fengrong, SHANG Xulan. A comparative study on leaf characters between diploid and tetraploid of Cyclocarya paliurus [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2024, 48(4): 76-84.
[15]	MA Tan, TIAN Ye, WANG Shujun, LI Wenhao, DUAN Qiying, ZHANG Qingyuan. Sex-specific leaf physiological responses of southern-type poplar to short-term intermittent soil drought [J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2024, 48(3): 172-180.

Metrics

Comments

www.nldxb.njfu.edu.cn

Edited ＆ Published by Editorial Department of Nanjing Forestry University(Natural Sciences Edition)
Address： No.159 Longpan Road,Nanjing 210037 Jiangsu,P.R.China
E-mail ：xuebao@njfu.edu.cn , xuebao@njfu.com.cn
Telephone +86-25-85428247,85427076
Distributed by China International Book Trading Corporation P.O. Box 399, Beijing ,P.R. China

A novel QTL mapping model for allometric growth and pleiotropic extension

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

Author

Reader

Reviewer