The research advances of pathogenic mechanism and controlling te.chnology for pine wood nematode disease are reviewed. In the research of the pathogen of the PWN disease, the viewpoint of most researchers is that the PWN act an important role in the disease. Some of. them think the PWN is the only pathogen, the few think both the PWN and the bacteria are the pathogens. There are three opinions about the pathogenetic mechanism of the PWN disease. (1) The cell of the pine is destructed by the cellulase from the PWN, which results in the pine death. (2) The toxin occurred by the tree after the PWN invaded affect the death. (3) The volatile material increased in xylem after the PWN invaded. The blockage of water conduction caused by tracheid cavitation was very important factor causing the death of infected pine trees. The resistance of pine to the PWN is evidently different in different species, and the resistance difference among the geographical population depends on the pine species.