Preparation and research of tebuconazole-loaded cellulose acetate 
slow-release formulation by high voltage electrostatic technology

doi:10.3969/j.issn.1000-2006.2016.06.018

JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2016, Vol. 59 ›› Issue (06): 117-121.doi: 10.3969/j.issn.1000-2006.2016.06.018

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Preparation and research of tebuconazole-loaded cellulose acetate slow-release formulation by high voltage electrostatic technology

XU Peng¹,GAO Juan²,WANG Liying²,LIANG Juan¹,TANG Jingen^2*

1.College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China;
2.College of Forestry, Nanjing Forestry University, Nanjing 210037, China

Online:2016-12-18 Published:2016-12-18

Abstract

Abstract: In this paper, the tebuconazole(TBA)was loaded on the cellulose acetate(CA)that is one of the biodegradable materials.The TBA-loaded microspheres and nano-fibers slow-release agents were prepared using the high voltage electrostatic technology. The release processes of the TBA-loaded microspheres and nano-fibers were also investigated. The structures and morphologies of the TBA-loaded microspheres and nano-fibers were characterized by the scanning electron microscopy, infrared spectrometer and laser particle size analyzer. Research results indicated that the concentration of cellulose acetate solution exerted a great influence on the structure of TBA release systems. The TBA-loaded microspheres were fabricated at a CA concentration of 4%, and the TBA-loaded nano-fibers were made at a CA concentration of 15%. Both the TBA-loaded microspheres and nano-fibers showed the slow-release property, and exerted definite antibacterial effect on the Candida albicans.

CLC Number:

S767

XU Peng,GAO Juan,WANG Liying,LIANG Juan,TANG Jingen. Preparation and research of tebuconazole-loaded cellulose acetate slow-release formulation by high voltage electrostatic technology[J]. JOURNAL OF NANJING FORESTRY UNIVERSITY, 2016, 59(06): 117-121.

References

[1] 刘建超, 贺红武, 冯新民. 化学农药的发展方向-绿色化学农药[J]. 农药, 2005, 44(1):1-3.Doi:10.3969/j.issn.1006.0413.2005.01.001. Liu J C, He H W, Feng X M. Direction of chemical pesticide development green chemical pesticides[J].Chinese Journal of Pesticides,2005, 44(1):1-3.
[2] Giroto A S, De Campos A, Pereira E I, et al. Study of a nanocomposite starch-clay for slow-release of herbicides: evidence of synergistic effects between the biodegradable matrix and exfoliated clay on herbicide release control[J]. Journal of Applied Polymer Science, 2014, 131(23):205-212.Doi:10.1002/app.41188.
[3] Ruggieri F, D'Archivio A A, Camillo D D, et al. Development of molecularly imprinted polymeric nanofibers by electrospinning and applications to pesticide adsorption[J]. Journal of Separation Science, 2015, 38(8):1402-1410.Doi:10.1002/jssc.20150033.
[4] 郑永权. 农药残留研究进展与展望[J]. 植物保护, 2013, 39(5):90-98.Doi:10.3969/j.issn.0529-1542.2013.05.012. Zheng Y Q. Development and prospects of the research on pesticide residue[J]. Plant Protection, 2013, 39(5):90-98.
[5] 华乃震. 农药剂型的进展和动向(上)[J]. 农药, 2008, 47(2):79-81. Doi:10.3969/j.issn.1006-0413.2008.02.001. Hua N Z. Advance and trend of pesticide formulation development[J]. Agrochemicals, 2008, 47(2):79-81.
[6] Zhao Y, Guo J J, Wu D W, et al. Photo-responsive shell cross-linked micelles based on carboxymethyl chitosan and their application in controlled release of pesticide[J]. Carbohydrate Polymers, 2015, 132:520-528.Doi:10.1016/j.carbpol.2015.06.077.
[7] 冯建国, 张小军, 于迟,等. 我国农药剂型加工的应用研究概况[J]. 中国农业大学学报, 2013, 18(2):220-226. Feng J G, Zhang X J, Yu C, et al. General situation of applied studies on pesticide formulations processing in China[J]. Journal of China Agricultural University, 2013, 18(2):220-226.
[8] 王彦华, 王鸣华, 张久双. 农药剂型发展概况[J]. 农药, 2007, 46(5):300-304.Doi:10.3969/j.issn.1006-0413.2007.05.003. Wang Y H, Wang M H, Zhang J S. Present situation on pesticide formulations[J]. Agrochemicals, 2007, 46(5):300-304.
[9] 周新华, 廖列文, 张志祥,等. 农药缓释微球的制备及其改性研究进展[J]. 农药, 2010, 49(12):862-867. Doi:10.3969/j.issn.1006-0413.2010.12.002. Zhou X H, Liao L W, Zhang Z X, et al. Progress on preparation and its modification of microspheres for slowrelease pesticides[J]. Agrochemicals, 2010, 49(12):862-867.
[10] 文朝霞, 席琛, 毛肖娟. 高分子材料在农药缓释剂中的应用[J]. 材料导报, 2014, 28(19):75-78. Wen Z X, Xi C, Mao X J. Application of polymers in pesticide release[J]. Materials Review, 2014, 28(19):75-78.
[11] 李北兴, 张大侠, 张灿光,等. 微囊化技术研究进展及其在农药领域的应用[J]. 农药学学报, 2014, 16(5):483-496. Doi:10.3969/j.issn.1008-7303.2014.05.01. Li B X, Zhang D X, Zhang C G, et al. Research advances and application prospects of microencapsulation techniques in pesticide[J]. Chinese Journal of Pesticide Science, 2014, 16(5):483-496.
[12] 周圆圆, 薛立伟, 毛吉富,等. 静电喷雾法制备聚膦腈微球[J]. 高分子学报, 2010, 31(1):125-130. Zhou Y Y, Xue L W, Mao J F, et al. Preparation of polyphosphazene microparticles via electrospray[J]. Acta Polymerica Sinica, 2010, 31(1):125-130.
[13] Jiang W L, Schwendeman S P. Stabilization and controlled release of bovine serum albumin encapsulated in poly(D,L-Lactide)and poly(Ethylene Glycol)microsphere blends[J]. Pharmaceutical Research, 2001, 18(6): 878-885.Doi:10.1023/A:1011009117586.
[14] Yang Y Y, Chung T S, Ng N P. Morphology, drug distribution, and in vitro release profiles of biodegradable polymeric microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method[J]. Biomaterials, 2001, 22(3):231-241.Doi:10.1016/S0142-9672(00)00178-2.
[15] Sukhorukov G B, Antipov A A, Voigt A, et al. pH-controlled macromolecule encapsulation in and release from polyelectrolyte multilayer nanocapsules[J]. Macromolecular Rapid Communications, 2001, 22(1):44-46.Doi:10.1002/1512-3927(20010101).
[16] Mu L, Feng S S. A novel controlled release formulation for the anticancer drug paclitaxel(Taxol): PLGA nanoparticles containing vitamin E TPGS[J]. Journal of Controlled Release, 2003, 86(1):33-48.Doi:10.1016/S0168-3659(02)00320-6.
[17] 高春朋, 高铭, 刘雁雁,等. 纺织品抗菌性能测试方法及标准[J]. 染整技术, 2007, 29(2):38-42. Doi:10.3969/j.issn.1005-9350.2007.02.012. Gao C P, Gao M, Liu Y Y, et al. Detection of antimicrobial activity for textiles[J]. Dyeing and Finishing Technology, 2007, 29(2)38-42.
[18] 鞠剑峰, 李澄俊, 徐铭. 纳米Ag/TiO₂复合微球和复合纳米纤维的抗菌性能[J]. 精细化工, 2005, 22(1):59-61. Ju J F, Li C J, Xu M. Antibacterial activity of nanocomposite Ag/TiO₂ material[J]. Fine Chemicals, 2005,22(1):59-61.
[19] 王娇娜, 马利婵, 李丽,等. 静电纺PES微球/纤维低阻力复合空气过滤膜的研究[J]. 高分子学报, 2014,(11):1479-1485. Doi:10.11777/j.issn/1000-3304.2014.14066. Wang J N, Ma L C, Li L, et al. PES microsphere /fiber low resistance composite air filter membranes prepared by electrostatic spinning[J]. Acta Polymerica Sinica, 2014,(11):1479-1485.
[20] Zhao D, Zhang Y, Lü L, et al. Preparation and release of avermectin-loaded cellulose acetate ultrafinefibers[J]. Polymer Engineering & Science, 2013, 53(3):609-614.Doi:10.1002/pen.23296.

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Preparation and research of tebuconazole-loaded cellulose acetate slow-release formulation by high voltage electrostatic technology

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