Preparation and research of tebuconazole-loaded cellulose acetate slow-release formulation by high voltage electrostatic technology

XU Peng,GAO Juan,WANG Liying,LIANG Juan,TANG Jingen

JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2016, Vol. 40 ›› Issue (06) : 117-121.

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JOURNAL OF NANJING FORESTRY UNIVERSITY ›› 2016, Vol. 40 ›› Issue (06) : 117-121. DOI: 10.3969/j.issn.1000-2006.2016.06.018

Preparation and research of tebuconazole-loaded cellulose acetate slow-release formulation by high voltage electrostatic technology

  • XU Peng1,GAO Juan2,WANG Liying2,LIANG Juan1,TANG Jingen2*
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Abstract

In this paper, the tebuconazole(TBA)was loaded on the cellulose acetate(CA)that is one of the biodegradable materials.The TBA-loaded microspheres and nano-fibers slow-release agents were prepared using the high voltage electrostatic technology. The release processes of the TBA-loaded microspheres and nano-fibers were also investigated. The structures and morphologies of the TBA-loaded microspheres and nano-fibers were characterized by the scanning electron microscopy, infrared spectrometer and laser particle size analyzer. Research results indicated that the concentration of cellulose acetate solution exerted a great influence on the structure of TBA release systems. The TBA-loaded microspheres were fabricated at a CA concentration of 4%, and the TBA-loaded nano-fibers were made at a CA concentration of 15%. Both the TBA-loaded microspheres and nano-fibers showed the slow-release property, and exerted definite antibacterial effect on the Candida albicans.

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XU Peng,GAO Juan,WANG Liying,LIANG Juan,TANG Jingen. Preparation and research of tebuconazole-loaded cellulose acetate slow-release formulation by high voltage electrostatic technology[J]. JOURNAL OF NANJING FORESTRY UNIVERSITY. 2016, 40(06): 117-121 https://doi.org/10.3969/j.issn.1000-2006.2016.06.018

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