Abstract: The overall flues of food, energy, water, material and wastes into and out of the Greater Jiangsu Area were studied quantificationally using material metabolism method. The most noticeable feature showed that outputs of solid wastes had generally increased at higher rates than inputs of solid material. Outputs of air emissions had generally increased at higher rates than inputs of fossil energy. Outputs of wastewater had generally increased at lower rates than inputs of fresh water. There was a positive correlation between outputs and inputs. The speed of the metabolism was higher and higher. The trends of material metabolism were escalating. Although all kinds of materials and energy had been used more efficiently, the ecological press on land, waters and atmosphere environment had not been reduced. Some pieces of policy advice also were given in this paper.