Abstract: To clear undertaking the future direction of CAZymes of filamentous fungi, the basic characteristics, classification and prediction methods, functions and other aspects of secreted protein and CAZymes of filamentous fungus were reviewed. Based on the previous reported literature about secreted protein and CAZymes of plant pathogenic filamentous fungus, the secreted protein and CAZymes were comprehensive analyzed by the method of bibliometric analysis, SMART conserved domain, motif analysis. And more specifically research on secreted protein in China, while research reports for CAZymes was less, at the same time, the function of most of secreted protein and CAZymes have not yet been fully analyzed during the pathogen infection. The prediction method of the secreted protein and CAZymes was basically based on bioinformatics analysis, and the protein with true function was screened to validate based on the evidence of biological experiment. Therefore, we need to further improve the prediction method of bioinformatics analysis tools or algorithms on the secreted protein and CAZymes, and to verify the protein with true function by carrying out biological experiments. And the commonness and characteristics were identified by the comparative analysis of the number and function of CAZymes between plant pathogens and microbial antagonist. In addition, the classification of CAZymes in filamentous fungi needs further refinement, and comparative analysis of the distribution of different subfamilies, which advance functional studies, provide an important theoretical basis.